产品货号：
Z17160
中文名称：
HAVCR1抗体
英文名称：
Anti-HAVCR1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HAVCR1 Antibody |
| 指标别名 | hepatitis A virus cellular receptor 1;CD365;HAVCR;HAVCR-1;KIM-1;KIM1;TIM;TIM-1;TIM1;TIMD-1;TIMD1 |
| 克隆性 | Polyclonal |
| 检验物种 | rat |
| 应用范围 | WB,IHC |
| 基因名称 | HAVCR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of rat TIM 1(289-307aa HPRAEDNIYIIEDRSRGAE). |
| 实际分子量 | 39KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | KIM1(KIDNEY INJURY MOLECULE 1),also known as HAVCR1,HAVCR or TIM1,is a protein that in humans is encoded by the KIM1 gene.The KIM1 gene is mapped to 5q33.3.Biochemical,mutational,and cell adhesion analyses confirm that Tim1 is capable of homophilic Tim-Tim interactions.The features identified in murine KIM1 is conserved in human KIM1.The KIM1 protein is indeed a receptor for the virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV.Using a monoclonal antibody to mouse Tim1,Tim1 is expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions.Ectopic expression of KIM1 during mouse T-cell differentiation leads to production of the Th2-type cytokine Il4,but not the Th1-type cytokine Ifng.KIM1-expressing epithelial cells internalized apoptotic bodies,and Kim1 is directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines. |
| Uniprot ID | O54947 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | hepatitis A virus cellular receptor 1 |
| 蛋白名全称 | Hepatitis A virus cellular receptor 1 homolog(HAVcr-1) |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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